Build a lane where Sett must walk forward
Opening lane until the first major recall, tower change, or objective contest changes the map
From the opening wave through your first meaningful recall or lane reset, make the matchup about wave position and Grit timing. Trade when Sett is last-hitting and has not stored much damage; avoid extended early fights inside his wave when Q and E are ready. Crash before recalling or rotating. If ahead, hold him on your side when you do not need to leave; if behind, take safe CS and XP, concede a trade when W would decide it, and wait for his key cooldowns.

Darius
Dr. Mundo
Garen
Gnar
Hecarim
Illaoi